Accelerate First-in-Human (FIH), SAD/MAD, and complex Phase I healthy volunteer or patient trials in our dedicated inpatient unit, with rapid recruitment and ICH-GCP compliant operations.
35+ years
350+ Phase I trials
15-bed unit
14000 subjects completed
FIH / SAD / MAD Phase I execution
Dedicated inpatient capacity
Healthy volunteers & Patient cohorts
Rapid feasibility & recruitment support
ICH-GCP compliant
Audit-ready operations
Decades of Regulatory Excellence and Human-Centric Clinical Trial Management.
Leverage decades of industry-leading expertise with our full-service CRO solutions, seamlessly managing your study from initial protocol design to the final Clinical Study Report (CSR). We ensure uncompromising ICH-GCP compliance to deliver high-fidelity data that accelerates your path to global market approval
Accelerate your study timelines with our data-driven feasibility assessments and proven access to a vast, diverse patient population. Our site-centric recruitment strategies ensure rapid enrolment targets are met under strict ICH-GCP standards, maintaining the highest levels of data integrity and subject safety.
Navigate complex regulatory landscapes with confidence through our proactive synergy with the National Drug Agency and Central Ethics Committees. We leverage deep institutional knowledge to deliver accelerated study start-up and streamlined approvals, ensuring your project remains compliant and on schedule
Streamline your early-phase development by integrating our specialized 15-bed Phase I unit with comprehensive CRO management under a single, transparent operational structure. This “under one roof” synergy allows for real-time data access and adaptive study pivots, significantly reducing overhead while maintaining uncompromising safety and precision
Our purpose-built, 15-bed clinical facility is equipped with the latest medical monitoring technology to support complex Phase I and Bioequivalence studies with surgical precision. Operating 24/7 under stringent safety protocols, our unit provides a controlled, high-performance environment designed to ensure subject welfare and the generation of clean, audit-ready data.
35 Years of Expertise
Patient-Centric Approach
US, EU & Asia Reach
With over 35 years of experience, we deliver the precision and integrity required for world-class clinical research. Working in seamless synergy with the National Drug Agency and the Central Ethics Committee, we ensure uncompromising compliance with the highest global regulatory standards.
Trusted partner for biotech & pharma leaders across the U.S., Western Europe, Israel, and China.
Consistently generating the high-quality clinical data essential for global regulatory success.
We don’t just execute trials; we build enduring collaborations based on reliability and results.
Conducting your clinical research in Bulgaria means operating within the full legal and ethical framework of the European Union, adhering strictly to EU Regulation 536/2014 and EMA standards. This unwavering commitment to international quality is the primary reason sponsors from across North America, Europe, and Asia trust us to deliver data that meets the most stringent global requirements.
Convex Ltd. is a private, family owned company with two main business divisions – clinical research management (CRO) and clinical research conduct (CRC). Convex CRO is a full-service Contract Research Organization (CRO in Bulgaria) that is devoted to small to mid- size pharmaceutical, biotechnology, generics, vaccines and nutrition companies with broad range of clinical research services in support of phase I to phase IV investigational drug and device development. Operating in Eastern Europe, Bulgaria as CRO and Phase 1 clinical research center, we provide hands-on versatility and flexibility, while adhering to the highest standards and providing quality service. Our smaller overhead, company structure and strategy allow for a leaner budget. For the past 30 years as one of the leading CROs in Eastern Europe, Bulgaria we managed to create a network of over 72 investigational sites including university and public hospitals, diagnostic consulting and medical and other private medical institutions.
We have extensive experience in conducting multicenter clinical trials in the following therapeutic areas: Oncology, Cardiology, Allergology, Pulmonology, Dermatology, Neurology, Endocrinology, Gastroenterology, Ophthalmology, Rheumatology, Gynecology, Rare diseases and Psychiatry. Convex CRO manages the entire clinical trial process. We have successfully completed over 280 clinical studies in given timelines and budget while focusing on integrity, transparency and excellence. Our capabilities cover A – Z clinical research services starting from: feasibility assessment, study teams and sites selection, budget management, contracts negotiation, medical writing, regulatory activities, investigator meeting organization, study startup support, study team training, project management, subjects recruitment, sites management, vendors management, clinical monitoring, safety reporting, auditing, data management, biostatistics, final report development and scientific consulting. Convex CRC is a clinical research center with a built-in phase I unit in which we have the capabilities and expertise to conduct clinical trials in early phases, as well as other types of studies.
The Clinical Research Center with pharmacology unit is focused on the conduct of single-center clinical trials on healthy volunteers and specific patient populations:
Our phase 1 unit is designed specifically for early-phase clinical studies, following the guidelines of the UK Medicines and Healthcare Products Regulatory Agency and the ICH-GCP. The stationary part of the unit accommodates 15 subjects for overnight stay. All essential facilities for storing study drugs, maintaining and storing study documentation, managing biological samples and handling emergency situations are available inside the unit. Specimens are seamlessly transferred for analysis to preferred bioanalytical lab or safety lab of your choice. Recruitment of subjects is facilitated significantly by the fact that the Clinical Research Center is strategically situated within a large metropolitan area, with access to population of over 2.5 million people. Our strongly developed network of referring General Practitioners and the availability of proactive recruitment specialists also brings a great benefit to successful recruiting achievements.
Hey, tell us about your clinical study and we’ll let you know how we can support you all the way
What clinical research services do we provide for your study?
Why do we see a return business from the same pharmaceutical companies or clinical trial sponsors over and over again?
How do I make sure my clinical study would be feasible to Convex clinical research center with Phase I pharmacology unit?
Let us know about your request at: feasibilityteam@convex.bg and we shall organize a TC to further discuss the progress of your study.
